Job Description
Scientist, Analytical Development
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Cambridge, MA
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6 month initial contract
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Pay: $45-48hr
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MUST BE A US CITIZEN (C2C and Visas/OPT not accepted)
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Top skills: chromatographic separation mechanisms in both gas phase and liquid phase and structure elucidation expertise. And MS experience.
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The Scientist, is part of Analytical Development Starting Material Group and will be responsible for
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•Develop, qualify and transfer GC, HPLC, UPLC and mass spectrometry based
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assays of starting materials, raw materials, intermediates and excipients to suppliers, CMOs and QC.
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• Identify impurity profiles and provide data to set impurity limits.
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•Understand and apply advanced scientific principles, theories, concepts, practices and standards to process and analytical development.
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Author and review method development and qualification reports and SOP’s for test methods, as well as transfer / qualification protocols and reports related to critical starting materials / intermediates / excipients.
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•Provide analytical support externally and internally.
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Qualifications
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•Ph.D. in Analytical Chemistry, Organic Chemistry or related disciplines with > 1 year biopharmaceutical experience or equivalent.
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•Master degree with > 5 years biopharmaceutical experience respectively, with
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demonstrated chromatographic separation, method development / qualification and structure elucidation expertise.
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•Strong knowledge of fundamental chromatographic separation mechanisms in both gas phase and liquid phase, proven years of excellent hands-on method development and optimization experience on HPLC, UPLC and GC for separation of molecules and isomers.
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•Sound background in organic chemistry with a focus on structure characterization and elucidation of synthetic molecules through determination and interpretation of mass spectrometry and NMR data.
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•Self-motivated, excellent communication, writing and reviewing skills.
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•Familiarity with Waters and Agilent (U)HPLC and Mass Spectrometery hardware.
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•Familiarity with Empower, Masslynx, Masshunter, and XCalibur CDS are preferred.
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•Experience in peptide and/or oligonucletide analysis is a plus